Univ.-Prof.in Priv.-Doz.in Dr.in med. Ramona Woitek, PhD

Head of the Research Group MIAAI (Medical Image Analysis & Artificial Intelligence)

Ramona Woitek completed her medical studies at the Medical University of Vienna in 2008, followed by a PhD in Clinical Neuroscience and a radiology residency at the Department of Biomedical Imaging and Image-guided Therapy at the Medical University of Vienna. Between 2017 and 2022, Univ.-Prof.

Ramona Woitek worked scientifically and clinically at the Department of Radiology at the University of Cambridge and Addenbrookes Hospital in Cambridge, UK, where she researched hyperpolarised carbon-13 MRI and radiomics and multiomics in breast and ovarian cancer.

Key publications

Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.

Ursprung S, Woitek R, McLean MA, Priest AN, Crispin-Ortuzar M, Brodie CR, Gill AB, Gehrung M, Beer L, Riddick ACP, Field-Rayner J, Grist JT, Deen SS, Riemer F, Kaggie JD, Zaccagna F, Duarte JAG, Locke MJ, Frary A, Aho TF, Armitage JN, Casey R, Mendichovszky IA, Welsh SJ, Barrett T, Graves MJ, Eisen T, Mitchell TJ, Warren AY, Brindle KM, Sala E, Stewart GD, Gallagher FA.

Cancers (Basel). 2022 Jan 11;14(2):335.

doi: 10.3390/cancers14020335.

Machine Learning for Workflow Applications in Screening Mammography: Systematic Review and Meta-Analysis.

Hickman SE, Woitek R, Le EPV, Im YR, Mouritsen Luxhøj C, Aviles-Rivero AI, Baxter GC, MacKay JW, Gilbert FJ.

Radiology. 2022 Jan;302(1):88-104.

doi: 10.1148/radiol.2021210391.

Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients.

Woitek R, McLean MA, Ursprung S, Rueda OM, Manzano Garcia R, Locke MJ, Beer L, Baxter G, Rundo L, Provenzano E, Kaggie J, Patterson A, Frary A, Field-Rayner J, Papalouka V, Kane J, Benjamin AJV, Gill AB, Priest AN, Lewis DY, Russell R, Grimmer A, White B, Latimer-Bowman B, Patterson I, Schiller A, Carmo B, Slough R, Lanz T, Wason J, Schulte RF, Chin SF, Graves MJ, Gilbert FJ, Abraham JE, Caldas C, Brindle KM, Sala E, Gallagher FA.

Cancer Res. 2021 Dec 1;81(23):6004-6017.

doi: 10.1158/0008-5472.CAN-21-1499.

Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer

Crispin-Ortuzar M*, Woitek R*, Moore E, Reinius M, Beer L, Bura V, Rundo L, McCague C, Ursprung S, Escudero Sanchez L, Martin-Gonzalez P, Mouliere F, Chandrananda D, Morris J, Goranova T, Piskorz AM, Singh N, Sahdev A, Pintican R, Zerunian M, Addley H, Jimenez-Linan M, Markowetz F, Sala E, Brenton JD.

*These authors contributed equally.

medRxiv 2021.07.22.21260982; Preprint.

doi: https://doi.org/10.1101/2021.07.22.21260982

3D deformable registration of longitudinal abdominopelvic CT images using unsupervised deep learning.

van Eijnatten M, Rundo L, Batenburg KJ, Lucka F, Beddowes E, Caldas C, Gallagher FA, Sala E, Schönlieb CB, Woitek R.

Comput Methods Programs Biomed. 2021 Sep;208:106261.

doi: 10.1016/j.cmpb.2021.106261.

The use of hyperpolarised 13C-MRI in clinical body imaging to probe cancer metabolism.

Woitek R, Gallagher FA.

Br J Cancer. 2021 Mar;124(7):1187-1198. Review.

doi: 10.1038/s41416-020-01224-6.

Ultrasound-guided targeted biopsies of CT-based radiomic tumour habitats: technical development and initial experience in metastatic ovarian cancer.

Beer L, Martin-Gonzalez P, Delgado-Ortet M, Reinius M, Rundo L, Woitek R, Ursprung S, Escudero L, Sahin H, Funingana IG, Ang JE, Jimenez-Linan M, Lawton T, Phadke G, Davey S, Nguyen NQ, Markowetz F, Brenton JD, Crispin-Ortuzar M, Addley H, Sala E.

Eur Radiol. 2021 Jun;31(6):3765-3772.

doi: 10.1007/s00330-020-07560-8.

Hyperpolarized 13C MRI of Tumor Metabolism Demonstrates Early Metabolic Response to Neoadjuvant Chemotherapy in Breast Cancer.

Woitek R, McLean MA, Gill AB, Grist JT, Provenzano E, Patterson AJ, Ursprung S, Torheim T, Zaccagna F, Locke M, Laurent MC, Hilborne S, Frary A, Beer L, Rundo L, Patterson I, Slough R, Kane J, Biggs H, Harrison E, Lanz T, Basu B, Baird R, Sala E, Graves MJ, Gilbert FJ, Abraham JE, Caldas C, Brindle KM, Gallagher FA.

Radiol Imaging Cancer. 2020 Jul 31;2(4):e200017.

doi: 10.1148/rycan.2020200017.

Tissue-specific and interpretable sub-segmentation of whole tumour burden on CT images by unsupervised fuzzy clustering.

Rundo L, Beer L, Ursprung S, Martin-Gonzalez P, Markowetz F, Brenton JD, Crispin-Ortuzar M, Sala E, Woitek R.

Comput Biol Med. 2020 May;120:103751.

doi: 10.1016/j.compbiomed.2020.103751.

Radiomics of computed tomography and magnetic resonance imaging in renal cell carcinoma-a systematic review and meta-analysis.

Ursprung S, Beer L, Bruining A, Woitek R , Stewart GD, Gallagher FA, Sala E.

Eur Radiol. 2020 Jun;30(6):3558-3566.

doi: 10.1007/s00330-020-06666-3.

Imaging breast cancer using hyperpolarized carbon-13 MRI.

Gallagher FA*, Woitek R*, McLean MA, Gill AB, Manzano Garcia R, Provenzano E, Riemer F, Kaggie J, Chhabra A, Ursprung S, Grist JT, Daniels CJ, Zaccagna F, Laurent MC, Locke M, Hilborne S, Frary A, Torheim T, Boursnell C, Schiller A, Patterson I, Slough R, Carmo B, Kane J, Biggs H, Harrison E, Deen SS, Patterson A, Lanz T, Kingsbury Z, Ross M, Basu B, Baird R, Lomas DJ, Sala E, Wason J, Rueda OM, Chin SF, Wilkinson IB, Graves MJ, Abraham JE, Gilbert FJ, Caldas C, Brindle KM.

*These authors contributed equally.

Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2092-2098.

doi: 10.1073/pnas.1913841117.